Cardiac (18)F-FDG PET/CT with heparin detects infective vegetation in a patient with mechanical valve replacement
Alisa Klaipetch1, Osamu Manabe, Noriko Oyama-Manabe
1Department of Radiology, Chiang Mai University, Chiang Mai, Thailand.
Abstract:
We report the usefulness of F-FDG PET/CT for the detection and therapy evaluation of the infective vegetation. A 64-year-old man with history of aortic valve replacement presented with 2 months of fever without identifiable cause. Echocardiogram showed no inflammation vegetation or abnormality of mechanical valve function. FDG PET/CT with 50 IU/kg IV heparin revealed focal uptakes near the mechanical aortic valve. After antibiotics therapy, fever was ameliorated, and FDG PET/CT findings showed markedly decreased uptake of the lesions. FDG PET/CT is a powerful tool to detect endocarditis even in patients with no anatomical abnormalities.
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