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[Estimation of the risk of upper digestive tract bleeding in patients with portal cavernomatosis]

M Couselo1, V Ibáñez, L Mangas

  • 1Hospital Infantil La Fe, Valencia. miguelcjerez@hotmail.com

Cirugia Pediatrica : Organo Oficial De La Sociedad Espanola De Cirugia Pediatrica
|November 20, 2012
PubMed

Insights

Children diagnosed with portal cavernoma face a significant risk of upper gastrointestinal bleeding (UGB). In this study, 77% experienced UGB, with a median time to first bleed of 314 days.

Area of Science:

  • Pediatric Gastroenterology
  • Hepatology
  • Vascular Malformations

Context:

  • Portal cavernoma, a rare vascular malformation of the portal vein, can lead to serious complications in children.
  • Upper gastrointestinal bleeding (UGB) is a primary concern in pediatric patients with portal cavernoma.
  • Limited data exists on the incidence and risk factors of UGB in this specific pediatric population.

Purpose:

  • To determine the risk of upper gastrointestinal bleeding (UGB) in children diagnosed with portal cavernoma.
  • To identify potential risk factors associated with UGB in pediatric portal cavernoma cases.
  • To analyze the incidence rate and survival time until the first bleeding event.

Summary:

  • A retrospective analysis of 13 pediatric portal cavernoma cases was conducted.
  • The study found a high incidence of UGB (77%) with a median time to first bleed of 314 days.
  • No statistically significant association was found between studied parameters (age, platelets, leukocytes, hemoglobin, hematocrit, prothrombin time) and UGB risk.

Impact:

  • Provides crucial data on the high risk of UGB in children with portal cavernoma.
  • Highlights the need for vigilant monitoring and management strategies for these patients.
  • Suggests further research is needed to identify predictive factors for bleeding events.
Abstract

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