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Intestinal Phase of Digestion

Intestinal Phase of Digestion

The intestinal phase of digestion is the third and final stage of the digestive process, occurring after the cephalic and gastric phases. It begins when chyme, a partially digested mixture of food and digestive enzymes, enters the small intestine from the stomach. This phase is crucial for nutrient absorption and involves complex hormonal and enzymatic interactions.
The arrival of the chyme in the small intestine distends the duodenum, which triggers the enterogastric reflex. This distension...

Kidney Transplant I: Introduction

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...

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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...

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Updated: May 16, 2026

Orthotopic Small Bowel Transplantation in Rats

Orthotopic Small Bowel Transplantation in Rats

Published on: November 6, 2012

[Intestinal transplant: in what phase are we?].

A M Andrés Moreno¹, E Ramos, F Hernández

¹Departamento de Cirugía Pediátrica, Sección de Trasplantes Digestivos, Hospital Infantil La Paz, Madrid. aneandresmo@hotmail.com

Cirugia Pediatrica : Organo Oficial De La Sociedad Espanola De Cirugia Pediatrica

|November 20, 2012

Summary

Pediatric intestinal transplantation offers a viable solution for irreversible intestinal failure, enabling patients to achieve a normal life. Continuous follow-up is crucial for managing immunological complications and improving long-term outcomes.

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Last Updated: May 16, 2026

Orthotopic Small Bowel Transplantation in Rats

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Published on: November 6, 2012

Tissue Engineering of the Intestine in a Murine Model

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Published on: December 1, 2012

A Rat Graft Rejection Model of Intestinal Transplantation with Exteriorized Ileostomy for Longitudinal Prognosis Assessment

A Rat Graft Rejection Model of Intestinal Transplantation with Exteriorized Ileostomy for Longitudinal Prognosis Assessment

Published on: June 10, 2025

Area of Science:

Pediatric surgery
Transplantation immunology
Gastroenterology

Context:

Intestinal transplantation is a complex procedure for children with irreversible intestinal failure.
The program's evolution from 1997 to 2009 involved 52 transplants in 46 children.
Indications included short gut syndrome, dismotility, and intractable diarrhea.

Purpose:

To analyze the evolution and outcomes of a pediatric small bowel transplantation program.
To evaluate patient and graft survival, quality of life, and complications.
To assess the impact of center experience on transplant results.

Summary:

Fifty-two intestinal transplants (isolated bowel, combined liver-intestine, multivisceral) were performed in 46 children.
Overall 5-year patient survival was 65.2% (graft survival 51.7%), with improved survival rates in recent years (2006-2008).
Long-term follow-up showed 59% of patients alive, off total parenteral nutrition (TPN), and enjoying a good quality of life.

Impact:

Intestinal transplantation is a consolidated option for irreversible intestinal failure, facilitating a normal life for pediatric patients.
Improved surgical techniques and immunosuppression management have enhanced transplant outcomes.
Close post-transplant monitoring is essential for early diagnosis and management of immunological complications.