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Related Concept Videos

CNS Depressants: Alcohol and Nicotine01:27

CNS Depressants: Alcohol and Nicotine

Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
Depressants01:28

Depressants

Depressant drugs, including alcohol and sedative-hypnotics, diminish central nervous system activity by enhancing the action of gamma-aminobutyric acid (GABA), a neurotransmitter that reduces brain activity and promotes relaxation. These substances can have various therapeutic uses but also pose significant risks, especially when misused or combined.
Alcohol is a common depressant that can induce a sense of relaxation and reduced inhibition at low doses. Contrary to its occasional...
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders01:27

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Diagnostic and Statistical Manual of Mental Disorders (DSM)01:27

Diagnostic and Statistical Manual of Mental Disorders (DSM)

The Diagnostic and Statistical Manual of Mental Disorders (DSM) serves as the primary classification system for mental health disorders, providing standardized diagnostic criteria for clinicians and researchers. First published by the American Psychiatric Association (APA) in 1952, the DSM has undergone several revisions to reflect evolving psychiatric understanding. The fifth edition, DSM-5, released in 2013, introduced key updates that expanded diagnostic categories and modified diagnostic...
Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

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Related Experiment Video

Updated: May 16, 2026

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
05:12

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

Published on: June 23, 2023

[Alcohol and psychiatric disorders].

Joanna Bouzyk-Szutkiewicz1, Napoleon Waszkiewicz, Agata Szulc

  • 1Medical University of Bialystok, Department of Psychiatry, Poland. joannabou@yahoo.com

Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego
|November 20, 2012
PubMed
Summary

Alcohol dependence and abuse cause significant social and economic burdens globally. Chronic alcohol abuse leads to severe physical and mental health issues, including brain damage and various psychiatric disorders.

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Last Updated: May 16, 2026

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
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Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication
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Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice
07:31

Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice

Published on: January 7, 2019

Area of Science:

  • Public Health
  • Neuroscience
  • Psychiatry

Context:

  • Alcohol dependence and abuse represent a major global health challenge with substantial social and economic costs.
  • Changing global drinking patterns, including increased heavy consumption by women and young people, necessitate broader medical attention.
  • Risky and chronic alcohol abuse pose significant health risks, leading to severe physical and mental complications.

Purpose:

  • To highlight the multifaceted health implications of alcohol dependence and abuse.
  • To outline the spectrum of alcohol-induced brain damage and associated neurological conditions.
  • To explore the frequent comorbidity between mental health disorders and alcohol abuse.

Summary:

  • Alcohol use disorders are linked to a range of alcohol-induced brain damages, such as withdrawal states, delirium tremens, alcoholic hallucinosis, paranoia, Korsakoff psychosis, dementia, and depression.
  • Mental health conditions including panic disorder, social anxiety disorder, agoraphobia, depression, bipolar disorder, schizophrenia, and personality disorders are frequently comorbid with or triggered by alcohol abuse.
  • The pervasive nature of alcohol abuse affects various medical specialties beyond psychiatry, underscoring its broad impact on public health.

Impact:

  • Increased awareness of the severe neurological and psychiatric consequences of alcohol abuse.
  • Emphasizes the need for integrated treatment approaches for comorbid alcohol and mental health disorders.
  • Informs public health strategies aimed at mitigating the social and economic burdens of alcohol dependence and abuse.