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Updated: May 16, 2026
Comprehensive Evaluation of the Effectiveness and Safety of Placenta-Targeted Drug Delivery Using Three Complementary Methods
Published on: September 10, 2018
[Comprehensive analysis of therapeutic methods and effect on cesarean scar pregnancy]
Hua-jiang Shao1, Jian-ting Ma, Li-ping Xu
1Department of Obstetrics & Gynecology, Yuyao People's Hospital, Yuyao 315400, China. yyphshj@163.com
Objective:
To evaluate the efficacies and medic economic efficiency of therapeutic method for cesarean scar pregnancy (CSP).
Methods:
The pertinent literatures on the treatment of CSP were collected and screened by retrieving some Chinese and English databases, such as PubMed, VIP and Wanfang Data. The weighting means and polled standard deviations of operative duration, operative hemorrhage volume, hysterectomy rate, length of stay, medical fees and the time of serum level of beta-human chorionic gonadotropin (β-HCG) returning to normal were reckoned.
Results:
Among different therapeutic methods of CSP, curettage duration was shortest in the patients with methotrexate (MTX) injection; operative hemorrhage volume, hysterectomy rate and length of stay were smallest in those with uterine artery embolization; medical fees was least in those with local MTX injection; the time of serum β-HCG level returning to normal was shortest in those with hysteroscopic and/or laparoscopic operation after MTX injection or uterine artery embolization.
Conclusion:
Curettage after uterine artery embolization offers multiple advantages over therapeutic methods in the treatment of CSP.
