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Related Concept Videos

Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Accessory Structures of the Eye01:17

Accessory Structures of the Eye

Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
Muscles of the Eye01:20

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The muscles of the eye are sophisticated structures that control eye movement and focus, allowing for the precise and rapid adjustments necessary for vision. The human eye is controlled by ten muscles — six extraocular muscles, three intraocular muscles, and one primary eyelid retractor muscle.
Extraocular Muscles
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Anatomy of the Eyeball

The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle layer, the vascular tunic,...
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Updated: May 16, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
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Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Primary synovial sarcoma in the orbit.

Ke Liu1, Xuanchu Duan, Liangchun Yang

  • 1Department of Ophthalmology, 2nd Xiangya Hospital, Central South University, China.

Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
|November 20, 2012
PubMed
Summary
This summary is machine-generated.

Synovial sarcoma, a rare soft-tissue tumor, typically affects young adults in their extremities. This report details the first documented case of primary orbital synovial sarcoma in an infant.

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Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
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Area of Science:

  • Oncology
  • Ophthalmology
  • Pathology

Background:

  • Synovial sarcoma is a rare malignant neoplasm, constituting 6-9% of soft-tissue tumors.
  • It predominantly affects the extremities of young adults.
  • Orbital involvement is exceptionally rare.

Observation:

  • This study presents the first reported case of primary orbital synovial sarcoma.
  • The patient was an 18-month-old girl.
  • The tumor was located in the orbit.

Findings:

  • The case confirms orbital synovial sarcoma can occur in pediatric patients.
  • Histopathological and molecular analyses confirmed the diagnosis.
  • This finding expands the known clinical spectrum of synovial sarcoma.

Implications:

  • Highlights the importance of considering rare soft-tissue tumors in orbital masses.
  • Suggests potential for earlier diagnosis and treatment in pediatric cases.
  • Contributes to understanding the diverse presentations of synovial sarcoma.