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Updated: May 16, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
50 practical medication tips at end of life
Mary Lynn McPherson1, Mina Kim, Kathryn A Walker
1University of Maryland School of Pharmacy, Hospice Pharmacist, Baltimore, MD 21201, USA. mmcphers@rx.umaryland.edu
Managing symptoms in life-limiting illnesses requires careful medication management. This guide provides practical tips for end-of-life medication therapy, including dosing, administration, and selection for complex cases.
Area of Science:
- Palliative Care
- Pharmacology
- Geriatric Medicine
Background:
- Patients with life-limiting illnesses often experience significant symptom burden, including pain.
- Effective symptom management is crucial for improving quality of life at the end of life.
- Medication therapy requires careful consideration due to evolving patient needs.
Purpose of the Study:
- To provide practical, evidence-based recommendations for end-of-life medication management.
- To offer guidance on creative approaches to medication selection, dosing, and administration.
- To address challenges in treating difficult-to-manage symptoms in palliative care.
Main Methods:
- Review of current literature and clinical best practices in end-of-life pharmacotherapy.
- Synthesis of practical strategies for medication administration and dosage adjustments.
- Discussion of alternative formulations and routes of administration.
- Consideration of specific medication regimens, including debridement therapies.
Main Results:
- Highlights the importance of individualized medication selection and administration.
- Offers strategies for dose escalation and de-escalation based on patient response.
- Discusses the use of alternative dosage forms and routes for improved efficacy and tolerability.
- Provides guidance on selecting appropriate drug therapies for complex symptom management.
Conclusions:
- Optimizing medication therapy is essential for effective symptom control in patients with life-limiting illnesses.
- Creative and flexible approaches to pharmacotherapy are necessary to meet individual patient needs.
- This article serves as a practical resource for clinicians managing end-of-life care.
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