Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Strategies for Assessing and Addressing Confounding01:25

Strategies for Assessing and Addressing Confounding

Confounding is a critical issue in epidemiological studies, often leading to misleading conclusions about associations between exposures and outcomes. It occurs when the relationship between the exposure and the outcome is mixed with the effects of other factors that influence the outcome. Given that, addressing confounding is of high importance for drawing accurate inferences in research.
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
Nursing Interventions II: Selecting and Classifying the Nursing Interventions01:29

Nursing Interventions II: Selecting and Classifying the Nursing Interventions

Creating and executing a nursing diagnosis helps nurses plan care and guide patient, family, and community interventions. They are developed based on a patient's physical evaluation and support measuring the outcomes. It is not recommended to select random interventions throughout the planning process. Instead, consider the following six essential factors when choosing interventions:
Guidelines for Writing Outcome01:11

Guidelines for Writing Outcome

When developing expected outcomes for a patient care plan, the nurse should adhere to the following recommendations:
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care evaluation by...
Study Designs in Epidemiology01:20

Study Designs in Epidemiology

Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and case-control studies.
Community Based Intervention01:30

Community Based Intervention

Community-based interventions in mental health represent a paradigm shift from institution-centered care to treatments embedded within the fabric of local communities. By prioritizing inclusion and leveraging existing societal structures, this approach fosters a supportive environment conducive to addressing mental health challenges while promoting individual dignity and agency.
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effectiveness of surveillance technology for the prevention of suicides in public spaces: a systematic review.

BMJ public health·2026
Same author

Impact of a non-contributory pension for older adults on hospitalisations and mortality: a protocol for a natural experimental study of the Brazilian continuous cash benefit (BPC).

BMJ open·2026
Same author

Evaluability assessment of a targeted national anti-child poverty policy: option appraisal for evaluating the Scottish Child Payment.

Health research policy and systems·2026
Same author

Road safety policies and motor vehicle fatalities in Ecuador: a geographical and temporal analysis from 1990 to 2022.

BMJ public health·2026
Same author

Reviewing ecosystems of evidence: synthesising the evidence on the commercial determinants of health from a complex systems perspective.

Systematic reviews·2026
Same author

Surveillance Technologies for Suicide Prevention in Public Places: A Scoping Review of Their Nature and Feasibility.

Archives of suicide research : official journal of the International Academy for Suicide Research·2026
Same journal

Effect of an enhanced recovery after surgery protocol for children with acute appendicitis: A randomized controlled trial.

International journal of nursing studies·2026
Same journal

Cognitive impairment, no dementia and hospitalizations - the role of formal and informal care: A population-based cohort study.

International journal of nursing studies·2026
Same journal

Rethinking occupational health and safety for healthcare workers treating Ebola.

International journal of nursing studies·2026
Same journal

Integrating fundamentals of care - moving from strategic intent to clinical practice: An organizational case study.

International journal of nursing studies·2026
Same journal

Observation of interprofessional collaborative practice in primary care teams: An updated integrative review.

International journal of nursing studies·2026
Same journal

Comparative effectiveness of individual-level psychosocial interventions for nurse burnout and its core dimensions: A systematic review and network meta-analysis.

International journal of nursing studies·2026
See all related articles

Related Experiment Video

Updated: May 16, 2026

Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting
06:16

Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting

Published on: June 6, 2020

Developing and evaluating complex interventions: reflections on the 2008 MRC guidance.

Peter Craig1, Mark Petticrew

  • 1Chief Scientist Office, Scottish Government Health Directorates, United Kingdom. peter.craig@scotland.gsi.gov.uk

International Journal of Nursing Studies
|November 20, 2012
PubMed
Summary
This summary is machine-generated.

This commentary reviews the Medical Research Council's (MRC) updated guidelines for developing and evaluating complex interventions. It also addresses critiques of the revised guidance, offering insights into ongoing scientific discourse.

More Related Videos

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

Related Experiment Videos

Last Updated: May 16, 2026

Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting
06:16

Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting

Published on: June 6, 2020

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

Area of Science:

  • Health Services Research
  • Intervention Science
  • Public Health Policy

Background:

  • The Medical Research Council (MRC) released revised guidance for complex interventions.
  • Complex interventions require specific methodologies for development and evaluation.
  • Previous guidance has been influential in the field.

Purpose of the Study:

  • To reflect on the impact of the MRC's revised guidance.
  • To consider published criticisms of the new guidance.
  • To contribute to the ongoing discussion on intervention science.

Main Methods:

  • This is an invited commentary, not an empirical study.
  • Analysis of the MRC's revised guidance document.
  • Synthesis of published critiques and responses.

Main Results:

  • The commentary highlights the significance of the revised MRC guidance.
  • It acknowledges and discusses key criticisms leveled against the guidance.
  • It identifies areas of debate and potential future directions.

Conclusions:

  • The revised MRC guidance presents both opportunities and challenges.
  • Critical engagement with the guidance is essential for advancing intervention science.
  • Further discussion is needed to refine best practices for complex interventions.