Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
Pericarditis I: Introduction01:22

Pericarditis I: Introduction

Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
Myocarditis I: Introduction01:21

Myocarditis I: Introduction

Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cardiac Computed Tomography for Prosthetic Heart Valve Assessment: An Expert Consensus Document of the Society of Cardiovascular Computed Tomography (SCCT), the American College of Cardiology (ACC), the European Society of Cardiovascular Radiology (ESCR), the North American Society of Cardiovascular Imaging (NASCI), the Radiological Society of North America (RSNA), the Society for Cardiovascular Angiography & Interventions (SCAI) and Society of Thoracic Surgeons (STS)<sup></sup>.

Journal of the American College of Cardiology·2025
Same author

Cardiac Computed Tomography for Prosthetic Heart Valve Assessment. An Expert Consensus Document of the Society of Cardiovascular Computed Tomography (SCCT), the American College of Cardiology (ACC), the European Society of Cardiovascular Radiology (ESCR), the North American Society of Cardiovascular Imaging (NASCI), the Radiological Society of North America (RSNA), the Society for Cardiovascular Angiography & Interventions (SCAI), and Society of Thoracic Surgeons (STS)<sup>1,2</sup>.

Radiology. Cardiothoracic imaging·2025
Same author

Cardiac computed tomography for prosthetic heart valve assessment. An expert consensus document of the Society of Cardiovascular Computed Tomography (SCCT), the American College of Cardiology (ACC), the European Society of Cardiovascular Radiology (ESCR), the North American Society of Cardiovascular Imaging (NASCI), the Radiological Society of North America (RSNA), the Society for Cardiovascular Angiography & Interventions (SCAI) and Society of Thoracic Surgeons (STS).

Journal of cardiovascular computed tomography·2025
Same author

Permanent Cardiac Pacing in the Fontan Population: A Contemporary Review of Indications, Approaches, and Outcomes.

JACC. Advances·2025
Same author

Splanchnic Nerve Block for Chronic Heart Failure.

JACC. Heart failure·2020
Same author

Addressing the Menace of Enterococcal Endocarditis.

Journal of the American College of Cardiology·2020
Same journal

The Influence of Congenital Heart Defect Repair Through a Right Subaxillary Thoracotomy on Postoperative Pulmonary Function and Prognosis in Small Infants.

Reviews in cardiovascular medicine·2026
Same journal

Left Ventricular Hypertrabeculation: Historical Evolution, Diagnostic Pitfalls, and a Pragmatic Clinical Approach.

Reviews in cardiovascular medicine·2026
Same journal

Study on the Role and Mechanism of γδ T Cells in Atherosclerosis Under a High-Fat Diet.

Reviews in cardiovascular medicine·2026
Same journal

The Role of Stress Granules in Cardiovascular Diseases.

Reviews in cardiovascular medicine·2026
Same journal

Computed Tomography-Based Radiomics Provides New Insights Into Associations Between Pericoronary Fat Characteristics and Low-Density Lipoprotein Cholesterol.

Reviews in cardiovascular medicine·2026
Same journal

Association of Triglyceride-Glucose Index With In-Hospital Malignant Arrhythmias in Older Patients With Diabetes Mellitus and Left Ventricular Aneurysm: A Retrospective Study.

Reviews in cardiovascular medicine·2026
See all related articles

Related Experiment Video

Updated: May 16, 2026

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues
07:50

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues

Published on: January 7, 2019

Infective endocarditis: a comprehensive overview.

Todd L Kiefer1, Thomas M Bashore

  • 1Division of Cardiology, Duke University Medical Center, Durham, NC, USA.

Reviews in Cardiovascular Medicine
|November 20, 2012
PubMed
Summary
This summary is machine-generated.

Infective endocarditis (IE), a heart valve infection, affects multiple organs and has high mortality. This review covers IE pathophysiology, diagnosis, management, and updated prophylaxis guidelines, including device-related infections.

More Related Videos

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus (MRSA) in Rat
07:46

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus (MRSA) in Rat

Published on: June 4, 2012

Related Experiment Videos

Last Updated: May 16, 2026

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues
07:50

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues

Published on: January 7, 2019

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus (MRSA) in Rat
07:46

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus (MRSA) in Rat

Published on: June 4, 2012

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Internal Medicine

Background:

  • Infective endocarditis (IE) involves infection of heart valves or cardiac devices.
  • IE can lead to severe complications affecting multiple organ systems.
  • Despite diagnostic advances, IE continues to have high morbidity and mortality rates.

Purpose of the Study:

  • To provide a comprehensive review of infective endocarditis (IE).
  • To discuss recent updates in IE pathophysiology, complications, diagnosis, and management.
  • To address intracardiac device-related IE and updated prophylaxis guidelines.

Main Methods:

  • Literature review of recent studies on IE.
  • Analysis of major cardiovascular society guidelines.
  • Focus on intracardiac device-related IE and prophylaxis.

Main Results:

  • IE pathophysiology involves endothelial damage and can affect cardiac devices.
  • Complications of IE are widespread, impacting various organ systems.
  • Updated guidelines address IE diagnosis, management, and prophylaxis, especially for device-related cases.

Conclusions:

  • Infective endocarditis remains a significant clinical challenge with high mortality.
  • Recent guideline updates provide crucial information for managing IE, particularly device-related infections.
  • Adherence to updated prophylaxis strategies is essential for preventing IE.