Cellular angiofibroma with atypia or sarcomatous transformation - case description with literature review

Cellular angiofibroma (CAF) is a rare, benign, mesenchymal tumor. It was first described by Nucci et al. in 1997 and then in 1998 by Laskin. The tumor occurs predominantly in the vulvo-vaginal or inguino-scrotal region. We present a 71-year-old male, who was referred to the Bielanski Hospital with a three months' history of a slowly growing nodule in the right groin. Gross examination showed a well-circumscribed tumor attached to the spermatic cord and measuring 6 cm in the greatest dimension. Microscopic examination of the tumor showed a spindle cell lesion with a loose, myxoid, partly collagenized stroma with numerous, prominent thick-walled vessels. Scattered atypical cells were present.