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Updated: May 16, 2026

09:44
Design, Synthesis, and Photochemical Properties of Clickable Caged Compounds
Published on: October 15, 2019
Light-addressable capsules as caged compound matrix for controlled triggering of cytosolic reactions
Markus Ochs1, Susana Carregal-Romero, Joanna Rejman
1Fachbereich Physik and WZWM, Philipps Universität Marburg, Germany.
Angewandte Chemie (International Ed. in English)
|November 20, 2012
Abstract:
Release me: polyelectrolyte capsules with different cargo in their cavities and plasmonic and magnetic nanoparticles in their walls were synthesized. Enzymatic reactions were triggered inside cells by light-mediated opening of two individual capsules containing either an enzyme or its substrate, by using photothermal heating. Furthermore, this technique allows controlled release of mRNA from capsules, thereby resulting in synthesis of green fluorescent protein (GFP).

