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Updated: May 16, 2026

In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model
Published on: October 27, 2020
Haematological, neurological and electrocardiographic findings in secondary hypothermia
Oana Dickinson1, Brian Hanson, David G Benditt
1Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA.
The association between secondary hypothermia and pancytopaenia is uncommon. A young woman presented with chronic hypothermia (28.8-34.6°C) secondary to surgical hypothalamic injury postcraniopharyingioma resection as a child. Associated findings included pancytopaenia (haemoglobin 8.1 g/dl, leucocytes 3500/mm(3), platelets 63,000/mm(3)), ataxia, upper motor neuron signs, decreased level of consciousness and new ECG changes. An extensive evaluation failed to reveal any cause of pancytopaenia other than chronic hypothermia. The haematological and neurological changes improved after active rewarming.
The association between secondary hypothermia and pancytopaenia is uncommon. A young woman presented with chronic hypothermia (28.8-34.6°C) secondary to surgical hypothalamic injury postcraniopharyingioma resection as a child. Associated findings included pancytopaenia (haemoglobin 8.1 g/dl, leucocytes 3500/mm(3), platelets 63,000/mm(3)), ataxia, upper motor neuron signs, decreased level of consciousness and new ECG changes. An extensive evaluation failed to reveal any cause of pancytopaenia other than chronic hypothermia. The haematological and neurological changes improved after active rewarming.
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