Related Experiment Video
Updated: May 16, 2026

Recording and Analyzing Multimodal Large-Scale Neuronal Ensemble Dynamics on CMOS-Integrated High-Density Microelectrode Array
Published on: March 8, 2024
Order Patterns Networks (ORPAN)-a method to estimate time-evolving functional connectivity from multivariate time
Stefan Schinkel1, Gorka Zamora-López, Olaf Dimigen
1Department of Physics, Humboldt-Universität zu Berlin Berlin, Germany ; Department of Psychology, Humboldt-Universität zu Berlin Berlin, Germany.
Abstract:
Complex networks provide an excellent framework for studying the function of the human brain activity. Yet estimating functional networks from measured signals is not trivial, especially if the data is non-stationary and noisy as it is often the case with physiological recordings. In this article we propose a method that uses the local rank structure of the data to define functional links in terms of identical rank structures. The method yields temporal sequences of networks which permits to trace the evolution of the functional connectivity during the time course of the observation. We demonstrate the potentials of this approach with model data as well as with experimental data from an electrophysiological study on language processing.

