Microangioarchitecture of gastric mucosa in man: antrum ventriculi

The blood vessels of the antrum area of human gastric tunica mucosa have been studied by scanning electron microscopy and compared with vertical and horizontal serial sections of perfusion-fixed antrum mucosa. In contrast to previous studies on the oxyntic corpus mucosa, where two superimposed capillary layers could be seen, the antrum mucosa presents only one capillary layer. It extends from the lymphatic follicles above the lamina muscularis mucosae up to the luminal surface. No further arterioles exist in the glandular part of the antrum mucosa. The luminal aspect of the capillaries show thin, honeycomb-like capillaries, differing from our previous findings in the corpus area. There the capillaries are wide and circulate in a dense, convoluted way. Arteriovenous anastomoses again could not be seen in the examined tissue. The differences in gastric microangioarchitecture might be explained by the extent of the glandular part in both regions. The findings in the antrum area very much resemble the basal capillary layer in the corpus mucosa. The critical height for one capillary layer in the glandular tissue of human gastric mucosa is estimated to be approximately 1 mm. Larger diameters, as in the oxyntic corpus mucosa, might require a second capillary layer.