Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Observations of cochlear microcirculation using intravital microscopy.

A Axelsson1, A L Nuttall, J M Miller

  • 1Department of Audiology, Sahlgren's Hospital, Göteborg, Sweden.

Acta Oto-Laryngologica
|March 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Determination of the source location of anthropogenic radionuclides collected in Finland and Sweden in June 2020 using a multi-technology analysis.

Journal of environmental radioactivity·2024
Same author

Third international challenge to model the medium- to long-range transport of radioxenon to four Comprehensive Nuclear-Test-Ban Treaty monitoring stations.

Journal of environmental radioactivity·2022
Same author

Outer hair cell driven reticular lamina mechanical distortion in living cochleae.

Hearing research·2021
Same author

Urologic, lymphedema, pelvic pain and gastrointestinal symptoms increase after radiotherapy in patients with primary uterine tumors: a prospective longitudinal Swedish cohort study.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·2021
Same author

Measurement of radioxenon and radioargon in soil gas collected in the region of Kvarntorp, Sweden.

Journal of environmental radioactivity·2020
Same author

A new method for analysis of beta-gamma radioxenon spectra.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2019
Same journal

Vasopressin type-2 receptor mRNA expressions in endolymphatic sac and temporal bone cT findings in Meniere's disease.

Acta oto-laryngologica·2026
Same journal

The impact of climate and environmental factors on the incidence of Bell's palsy: a nationwide population study.

Acta oto-laryngologica·2026
Same journal

Association between low temporalis muscle thickness and chemoradiotherapy-induced leukopenia in head and neck squamous cell carcinoma.

Acta oto-laryngologica·2026
Same journal

Auditory Outcomes After Simultaneous Translabyrinthine Vestibular Schwannoma Resection and Cochlear Implantation: A Prospective Case Series.

Acta oto-laryngologica·2026
Same journal

CT imaging parameters of the oval window region can predict the extent of stapes footplate exposure in patients with otosclerosis.

Acta oto-laryngologica·2026
Same journal

Congenital middle ear anomalies: endoscopic outcomes, facial nerve anomalies, and bilateral consistency in 41 ears.

Acta oto-laryngologica·2026
See all related articles

This study visualizes guinea pig cochlear blood flow using advanced microscopy. Researchers observed consistent blood flow patterns even at low blood pressures, providing insights into cochlear microcirculation.

Area of Science:

  • Otoacoustic emissions
  • Auditory neuroscience
  • Vascular biology

Background:

  • The cochlea's unique vascular system is crucial for auditory function.
  • Understanding cochlear blood flow dynamics is vital for diagnosing and treating hearing disorders.
  • Previous studies have lacked detailed in vivo visualization of cochlear microvasculature.

Purpose of the Study:

  • To visually observe and quantify blood flow in guinea pig cochlear vessels.
  • To investigate the stability of cochlear blood flow under physiological stress.
  • To analyze changes in blood velocity during specific interventions.

Main Methods:

  • Fluorescence intravital microscopy was employed for real-time visualization.
  • Observation focused on lateral wall vessels in the first and third cochlear turns.

Related Experiment Videos

  • Blood velocity was measured during controlled hypotension and pentoxifylline perfusion.

    • Main Results:

    • A stable and consistent pattern of cochlear blood flow was maintained.
    • Blood flow remained consistent even at mean arterial blood pressures below 20 mmHg.
    • Changes in blood velocity were observed during pentoxifylline perfusion and exsanguination.

    Conclusions:

    • The guinea pig cochlea exhibits robust microcirculatory regulation.
    • Intravital microscopy provides a valuable tool for studying cochlear vascular physiology.
    • These findings contribute to understanding the mechanisms underlying cochlear blood flow and its potential disruption.