Related Experiment Video
Updated: May 16, 2026

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
Published on: January 12, 2022
Evaluation of the impact of uveitis on visual-related quality of life
Petrina Tan1, Yan Tong Koh, Poh Ying Wong
1National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Republic of Singapore. petrina_tan@ttsh.com.sg
Purpose:
To determine quality of life in patients with uveitis and investigate the association between clinical parameters of uveitis and visual functioning.
Methods:
Prospective cross-sectional study. The interviewer- administered National Eye Institute visual function questionnaire (VFQ-25) was used in 117 adult outpatient uveitic patients. Their scores were compared against 48 controls with no ocular history. Subgroup differences amongst the patients were compared using Mann-Whitney and Kruskal-Wallis test. Multiple regression analysis was performed to determine the associations of visual function and disease characteristics of uveitis.
Results:
VFQ-25 composite scores for patients were significantly lower than controls in all domains except driving. In multivariable analysis, lower VFQ-25 composite scores were associated with a chronic course of disease, even after taking into account the influences of visual acuity, treatment regimes and location of disease.
Conclusions:
Uveitic patients reported poorer visual functioning. A chronic course of disease is associated with poorer functioning.
Related Concept Videos
Glaucoma: Overview
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Nephrotic Syndrome II : Assessment and Medical Management
Angle Closure Glaucoma: Treatment