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Updated: May 16, 2026

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
CM-AVM syndrome in a neonate: case report and treatment with a novel flow reduction strategy
Gerald G Behr1, Leonardo Liberman2, Jocelyn Compton3
1Department of Radiology, Division of Pediatric Radiology Columbia University, New York, NY, USA.
Abstract:
Mutations in the RASA-1 gene underlie several related disorders of vasculogenesis. Capillary malformation-arteriovenous malformation (CM-AVM) is one such entity and was recently encountered in a neonate who demonstrated its clinical and radiologic features. A single mutation in the RASA-1 gene was detected.A novel flow reduction strategy was employed to a large AVM affecting the patient's upper limb. The imaging findings, surgical procedure and patient's improved post-operative state are described.
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