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Acute appendicitis in two children with Henoch-Schönlein purpura
Salim Bilici1, Cihangir Akgun, Mehmet Melek
1Departments of Pediatric Surgery, Yuzuncu Yil University School of Medicine, Van, Turkey.
Insights
Henoch-Schönlein purpura (HSP) can cause abdominal pain mimicking appendicitis. Rare cases of HSP with suppurative appendicitis highlight the need for thorough investigation in affected children.
Area of Science:
- Pediatric Gastroenterology
- Pediatric Surgery
- Rheumatology
Background:
- Henoch-Schönlein purpura (HSP) is a systemic vasculitis often affecting the gastrointestinal tract.
- Gastrointestinal involvement in HSP can present with abdominal pain, mimicking surgical emergencies like appendicitis.
Observation:
- Two pediatric cases are presented: a 13-year-old boy and a 12-year-old girl, both with HSP and abdominal pain.
- Despite initial treatment for HSP, both patients underwent laparotomy revealing acute suppurative appendicitis.
- Vasculitic lesions were noted in the ileum of both patients, suggesting a link between HSP and appendiceal inflammation.
Findings:
- Suppurative appendicitis is a rare but significant complication of Henoch-Schönlein purpura.
- Ileal and colonic vasculitis in HSP can present with symptoms indistinguishable from acute appendicitis.
- Standard HSP treatment did not resolve the appendicitis symptoms in these cases.
Implications:
- Clinicians should consider suppurative appendicitis in pediatric patients presenting with HSP and abdominal symptoms.
- Diagnostic imaging, such as ultrasonography, is crucial for differentiating HSP-related gastrointestinal issues from appendicitis.
- Early and accurate diagnosis is vital to prevent unnecessary appendicectomy and ensure appropriate management of HSP complications.
Abstract:
In Henoch-Schönlein purpura (HSP), involvement of the ileum and ascending colon with vasculitis can mimic appendicitis and cause unnecessary appendicectomy. A 13-year-old boy presented with signs of HSP and abdominal pain. He was treated with prednisolone (2 mg/kg/day) for 10 days, but there was no improvement. At laparotomy he had acute suppurative appendicitis. A 12-year-old girl presented with HSP associated with abdominal pain and bloody diarrhoea and at laparotomy was also found to have suppurative appendicitis. Both patients had vasculitic areas in the ileum. In HSP, although suppurative appendicitis is rare, it should always be considered and appropriate investigations, including ultrasonography, undertaken.
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