Related Experiment Video
Updated: May 16, 2026

Purification of a High Molecular Mass Protein in Streptococcus mutans
Published on: September 14, 2019
A novel biotechnology product for the degradation of biofilm-associated polysaccharides produced by Streptococcus
G Di Bonaventura1, M Uriani, A Fabbri
1Department of Biomedical Sciences, University of Chieti-Pescara, Chieti, Italy.
Abstract:
In this study we evaluated the activity of ABR preparation, a first-in-class agent obtained through fermentation process by genetically unmodified Bacillus spp., in breaking down polysaccharide produced by Streptococcus mutans, primary coloniser of tooth surface and abundant in dental biofilms. Our results showed that ABR preparation is able in degrading sugars formed by S. mutans, both in broth culture and onto teeth surface. Its activity is not influenced by the presence of saliva, commercial mouthwashes or oral disinfectants. ABR preparation has the potential to remove preformed plaque and counteract its development, thus offering conservative control of gingival and periodontal disease.
More Related Videos
11:09An Analytical Tool-box for Comprehensive Biochemical, Structural and Transcriptome Evaluation of Oral Biofilms Mediated by Mutans Streptococci
Published on: January 25, 2011
09:39A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries
Published on: December 27, 2016
Related Concept Videos
Biofilms
Bioplastics
Gene Regulation in Microbial Communities: Quorum Sensing
Clinical Significance of Antibiotic Resistance