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Related Experiment Video

Updated: May 16, 2026

Murine Fetal Echocardiography

Murine Fetal Echocardiography

Published on: February 15, 2013

[Double outlet right ventricle. Embryological approach].

Luis Muñoz-Castellanos¹, Magdalena Kuri

¹Departamento de Embriología, Instituto Nacional de Cardiología Ignacio Chávez, México D.F., México. munoz-embriologia@hotmail.com

Archivos De Cardiologia De Mexico

|November 21, 2012

Summary

Double outlet right ventricle arises from persistent embryonic right ventricular outflow tract continuity. Anatomical variations result from progressive detortion and torsion of the truncoconal septum.

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In Vitro Model of Coronary Angiogenesis

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Published on: March 10, 2020

Area of Science:

Congenital heart disease research
Embryological development of the heart
Cardiac morphology and anatomy

Context:

Double outlet right ventricle (DORV) is a complex congenital heart defect.
Understanding the morphogenesis of DORV anatomical variants is crucial for diagnosis and treatment.
Previous explanations for DORV morphogenesis lacked detailed embryological correlation.

Purpose:

To propose a pathogenetic explanation for the morphogenesis of anatomical variants of double outlet right ventricle.
To correlate embryological development with the anatomical variations observed in DORV.
To quantify the torsion of the truncoconal septum in different DORV subtypes.

Summary:

A comparative anatomical embryological analysis was performed on 35 hearts with DORV.
The study compared the truncoconal septum in DORV variants (slightly crossed, side-by-side, anterior aorta) with the normal embryonic heart.
Truncoconal septum torsion was calculated, revealing specific degrees of rotation for each anatomical variant.

Impact:

Provides a pathogenetic explanation for DORV based on embryological development.
Elucidates the role of truncoconal septum detortion and torsion in creating DORV anatomical variations.
Contributes to a deeper understanding of congenital heart defects, potentially aiding in future clinical management.