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Updated: May 16, 2026
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Published on: February 23, 2024
Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study
Pil Seok Chae1, Rohini R Rana, Kamil Gotfryd
1Department of Bionano Engineering, Hanyang University, Ansan, 426-791, Korea. pchae@hanyang.ac.kr
Abstract:
The development of a new class of surfactants for membrane protein manipulation, "GNG amphiphiles", is reported. These amphiphiles display promising behavior for membrane proteins, as demonstrated recently by the high resolution structure of a sodium-pumping pyrophosphatase reported by Kellosalo et al. (Science, 2012, 337, 473).
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