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Updated: May 16, 2026

Surgical Closure of Equine Abdomen, Prevention, and Management of Incisional Complications
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Antimicrobial use in horses undergoing colic surgery.

B L Dallap Schaer1, J K Linton, H Aceto

  • 1Department of Clinical Studies New Bolton Center, University of Pennsylvania School of Veterinary Medicine, Kennett Square, PA 19348, USA. bldallap@vet.upenn.edu

Journal of Veterinary Internal Medicine
|November 22, 2012
PubMed
Summary

Antimicrobial prophylaxis in horses undergoing colic surgery is often inappropriate, with poor adherence to guidelines. Improving perioperative antimicrobial use could reduce postoperative complications and improve outcomes.

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Area of Science:

  • Veterinary Surgery
  • Equine Medicine
  • Pharmacology

Background:

  • Antimicrobial prophylaxis guidelines are established for human surgery but less defined for veterinary practice.
  • Limited data exists on antimicrobial use patterns in horses undergoing emergency colic surgery.

Purpose of the Study:

  • To characterize antimicrobial administration practices in horses undergoing emergency colic surgery.
  • To evaluate the association between antimicrobial use and postoperative complications.

Main Methods:

  • Retrospective case review of 761 horses undergoing emergency colic surgery (2001-2007).
  • Data collected included antimicrobial dose, timing, surgical details, and treatment duration.
  • Statistical analysis (rank-sum, logistic regression) assessed links between antimicrobial use and outcomes like fever, infection, and Salmonella shedding.

Main Results:

  • A significant majority of horses (67.2%) received incorrect preoperative antimicrobial doses.
  • Intraoperative redosing was inadequate, with only 1.8% of horses receiving correct doses when indicated by surgery duration.
  • Reinstatement of antimicrobial therapy was associated with increased odds of fever, incisional infection, and Salmonella shedding.

Conclusions:

  • Compliance with established antimicrobial prophylaxis recommendations is poor in equine colic surgery.
  • Inappropriate antimicrobial use is linked to increased postoperative complications.
  • Optimizing perioperative antimicrobial strategies may enhance surgical outcomes in horses.