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Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
11:12

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation

Published on: July 16, 2014

Deep brain stimulation in Parkinson's disease: reconciliation of evidence-based medicine with clinical practice

Paul Krack1, Marwan I Hariz

  • 1Department of Psychiatry and Neurology, University Hospital of Grenoble, 38043 Grenoble, France. paul.krack@ujf-grenoble.fr

The Lancet. Neurology
|November 22, 2012
PubMed
Abstract

No abstract available in PubMed .

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Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of its...