Related Experiment Video
Updated: Aug 7, 2026

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
Published on: April 20, 2018
Syringosquamous metaplasia. A distinctive eruption in patients receiving chemotherapy
1Department of Dermatology, Boston University School of Medicine, Massachusetts 02118-2394.
Abstract:
Squamous metaplasia of the upper portion of the sweat ducts has been observed in four patients who received chemotherapy; two patients with acute myelogenous leukemia, one patient with testicular carcinoma, and one patient with anaplastic carcinoma of the lung. This change is different (but perhaps related) from what is described in neutrophilic eccrine hidradenitis in patients with acute myelogenous leukemia and other tumors after chemotherapy. Syringosquamous metaplasia may be confused with well differentiated squamous cell carcinoma histologically.
Related Concept Videos
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Cellular Adaptation IV: Dysplasia and Metaplasia

