Related Experiment Video
Updated: May 16, 2026
Robotic-assisted Bronchoscopy Combined with Multimodal Imaging for Targeted Lung Cryobiopsies
Published on: July 19, 2024
Technical advances: measurement of collateral flow in the lung with a dedicated endobronchial catheter system
Surag Mantri1, Chris Macaraeg, Sujith Shetty
1*Pulmonx, Inc, Palo Alto, CA †Department of Pneumology and Critical Care Medicine, Thoraxklinik, University of Heidelberg, Germany ‡Department of Interventional Pulmonology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.
Abstract:
Interest in assessment of collateral flow measurement has resurfaced with the advent of endoscopic lung volume reduction studies, namely valve technologies (eg Emphasys EBV), that achieve volume reduction through lobar isolation. It is currently thought that collateral ventilation could be a contributing factor for endoscopic lung volume reduction failures, as isolated lobes can "backfill" through these channels. In an attempt to quantify collateral ventilation, the Chartis System has been developed by Pulmonx, Inc. to measure pressure and flow, and calculate resistance to airflow through collateral channels in isolated lung compartments.