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Published on: May 20, 2019
Endobronchial instillations of amphotericin B: complementary treatment for pulmonary mucormycosis
Inmaculada Alfageme1, Angela Reina, Javier Gallego
1*Respiratory Unit †Department of Hematology, Valme University Hospital, Seville, Spain.
Abstract:
Pulmonary mucormycosis is a rare fungal infection that appears in patients with hematologic diseases who are immunosuppressed by chemotherapy. We report a case of pulmonary mucormycosis in a 21-year-old man with acute lymphoblastic leukaemia. During the period of pancytopenia he developed invasive mucormycosis. His initial symptoms were pleuritic chest pain with fever and unresponsiveness to broad-spectrum antibiotics. The outcome was favorable after long-term systemic and aerosolized amphotericin B, endobronchial instillations of amphotericin B, posaconazole, and surgery.
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