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Related Concept Videos

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Trachea01:22

Trachea

The trachea, commonly known as the windpipe, is a vital part of the human respiratory system. It serves as a passageway for air to travel between the larynx and the bronchi, allowing oxygen to reach the lungs. Let's explore its anatomical features, dimensions, layers of the tracheal wall, associated muscles, and the functions of its parts.
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of the...
The Bronchial Tree01:23

The Bronchial Tree

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Chronic Obstructive Pulmonary Disease II: Emphysema01:23

Chronic Obstructive Pulmonary Disease II: Emphysema

Emphysema, a major phenotype of chronic obstructive pulmonary disease (COPD), is characterized by irreversible destruction of alveolar walls and permanent enlargement of distal airspaces. Unlike chronic bronchitis, which primarily affects the airways, emphysema predominantly involves the lung parenchyma, where structural damage leads to airflow limitation.PathophysiologyIt most commonly results from prolonged exposure to cigarette smoke and other toxic gases, particularly cigarette smoke.
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...

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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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Tracheobronchial rhinoscleroma.

Mohamed Herrag1, Saâd Lahmiti, Abdelhaq Alaoui Yazidi

  • 1Department of Respiratory Disease, Mohammed VI University Hospital Marrakesh, Marrakesh's School of Medicine, Cadi Ayyad University, Morocco.

Journal of Bronchology & Interventional Pulmonology
|November 22, 2012
PubMed
Summary
This summary is machine-generated.

Rhinoscleroma, a chronic infection by Klebsiella rhinoscleromatis, can affect the larynx and tracheobronchial tree. This case highlights recurrent respiratory infections as a symptom of this rare upper airway disease.

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Area of Science:

  • Infectious Diseases
  • Respiratory Medicine
  • Microbiology

Background:

  • Rhinoscleroma is a chronic granulomatous infectious disease.
  • It is caused by the bacterium Klebsiella rhinoscleromatis.
  • Typically, it affects the nasal cavity and upper respiratory tract.

Purpose of the Study:

  • To report an unusual case of rhinoscleroma.
  • To describe the extension of rhinoscleroma to the larynx and tracheobronchial tree.
  • To highlight recurrent respiratory infection as a presenting symptom.

Main Methods:

  • Case report.
  • Clinical presentation review.
  • Diagnostic procedures (details not provided in abstract).

Main Results:

  • The patient presented with recurrent respiratory infections.
  • Rhinoscleroma was found to involve the larynx and tracheobronchial tree.
  • This represents an extended manifestation of the disease beyond the typical nasal site.

Conclusions:

  • Rhinoscleroma can present with atypical lower respiratory tract involvement.
  • Recurrent respiratory infections may indicate advanced or unusual rhinoscleroma.
  • Awareness of these extended presentations is crucial for diagnosis and management.