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Related Experiment Video

Updated: May 16, 2026

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease

Published on: January 20, 2010

Tracheopathia osteochondroplastica: two unusual cases.

Mustafa Erelel¹, Fatih Yakar, Zuleyha Kaya Bingol

¹Department of Pulmonary Medicine, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey.

Journal of Bronchology & Interventional Pulmonology

|November 22, 2012

Summary

Tracheopathia osteochondroplastica (TPO) is a rare condition. This study highlights two unusual TPO cases, one co-occurring with lung cancer and another in a young patient, emphasizing TPO in persistent cough differential diagnosis.

Related Experiment Videos

Last Updated: May 16, 2026

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease

Published on: January 20, 2010

Area of Science:

Medicine
Pulmonology
Pathology

Background:

Tracheopathia osteochondroplastica (TPO) is a rare condition characterized by osteochondromas in the trachea.
TPO typically affects middle-aged to older men, with symptoms often mimicking chronic bronchitis.

Purpose of the Study:

To report two uncommon cases of TPO.
To highlight the importance of considering TPO in patients with persistent respiratory symptoms, especially when conventional treatments fail.

Main Methods:

Case report of two patients diagnosed with TPO.
Diagnostic procedures included chest computed tomography (CT) and flexible bronchoscopy with histologic analysis.

Main Results:

Case 1: A 74-year-old man with TPO and coexisting squamous cell lung carcinoma.
Case 2: A young man presenting with TPO and persistent cough and dyspnea.

Conclusions:

TPO can present at uncommon ages and may coexist with other serious conditions like lung cancer.
Persistent cough and dyspnea, unresponsive to treatment, warrant investigation for rare tracheobronchial pathologies such as TPO.