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Updated: May 16, 2026

A Method of Nodose Ganglia Injection in Sprague-Dawley Rat
Published on: November 25, 2014
[Treatment of apomorphine infusion adverse effects: subcutaneous nodules and neuropsychiatric complications]
Verónica Giménez de Béjar1, Manuel Carballo-Cordero
1Hospitales Universitarios Virgen del Rocio, 41013 Sevilla, Espana.
Abstract:
Subcutaneous nodules and neuropsychiatric complications are the most relevant adverse effects during apomorphine infusion treatment. Subcutaneous nodules appear in almost all the patients and accurate information and training of both patient and caregiver is essential to minimise their impact on the treatment. Although neuropsychiatric complications are not more frequent than with other dopaminergic treatments, they are linked with increasing difficulty of treatment and worsening of patient's quality of life.
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