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Nodular duodenitis and single duodenal nodules.
J H Fernandez-Melone1, G Triadafilopoulos, J G Chandler
1Department of Surgery, University of California, Davis 94602.
The American Surgeon
|March 1, 1990
Summary
Nodular duodenitis, a common finding, often indicates inflammation. Single duodenal nodules are rare and may indicate tumors, requiring biopsy for diagnosis.
Area of Science:
- Gastroenterology
- Pathology
Background:
- Duodenal nodules are uncommon endoscopic findings.
- They are generally associated with duodenal inflammation.
Purpose of the Study:
- To examine the incidence and histologic correlates of multiple and single duodenal nodules.
- To differentiate nodular duodenitis from single duodenal nodules.
Main Methods:
- Retrospective analysis of 2,966 male patients undergoing esophagogastroduodenoscopy.
- Histologic examination of duodenal nodule biopsies.
Main Results:
- Duodenal nodules were found in 5% of patients.
- Nodular duodenitis (≥2 nodules) was 5.5 times more frequent than single nodules.
- Single nodules had a significant neoplastic potential, with tumors found in 5 of 23 patients.
Conclusions:
- Nodular duodenitis is a distinct variant of nonspecific duodenitis.
- Single duodenal nodules are less likely inflammatory and have significant neoplastic potential, necessitating biopsy.