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Related Concept Videos

Growth of Cartilage and Bone Tissue01:27

Growth of Cartilage and Bone Tissue

Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...
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Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...

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Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
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Chondroid syringoma with marked calcification.

Hee Jin Jun1, Eujin Cho, Sang Hyun Cho

  • 1Department of Dermatology, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

The American Journal of Dermatopathology
|November 22, 2012
PubMed
Summary
This summary is machine-generated.

Chondroid syringoma, a rare skin neoplasm, typically presents as either apocrine or eccrine types. This report details the first documented case of an apocrine type chondroid syringoma exhibiting calcification.

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Area of Science:

  • Dermatopathology
  • Oncology
  • Histology

Background:

  • Chondroid syringoma is a rare, benign skin neoplasm.
  • It comprises epithelial and myoepithelial cells within a mucoid/cartilaginous matrix.
  • Classified into apocrine and eccrine types.

Observation:

  • Several cases of eccrine type chondroid syringoma with ossification and calcification are documented.
  • Apocrine type chondroid syringoma with calcification has not been previously reported.
  • This report presents a unique case of apocrine type chondroid syringoma with calcification.

Findings:

  • The study describes a rare instance of apocrine type chondroid syringoma.
  • The neoplasm exhibited calcification, a feature not previously observed in this subtype.
  • Histopathological analysis confirmed the diagnosis.

Implications:

  • This finding expands the known spectrum of chondroid syringoma presentations.
  • It may necessitate re-evaluation of diagnostic criteria for apocrine type chondroid syringoma.
  • Further research into the pathogenesis of calcification in apocrine tumors is warranted.