Related Experiment Video
Updated: May 16, 2026

Single-throughput Complementary High-resolution Analytical Techniques for Characterizing Complex Natural Organic Matter Mixtures
Published on: January 7, 2019
Totally organic biphasic solvent systems for extraction and descriptor determinations
Colin F Poole1, Thushara Karunasekara, Thiloka C Ariyasena
1Department of Chemistry, Wayne State University, Detroit, MI, USA. cfp@chem.wayne.edu
Abstract:
Partition between two immiscible solvents is widely used in sample preparation procedures for matrix simplification and isolation of target analytes, for separations using countercurrent, centrifugal partition, and liquid-liquid chromatography, and as a method for determining descriptors for use in modeling chemical, biological, and environmental processes. Until recently, most applications employed water as one component of the biphasic system. For compounds of low water solubility or stability, a series of totally organic biphasic systems have been developed to enhance the application range of liquid-liquid partition methods. These systems, their characterization using the solvation parameter model, and applications to sample preparation and the determination of descriptors are described in this review.
More Related Videos
11:17A Simple Fractionated Extraction Method for the Comprehensive Analysis of Metabolites, Lipids, and Proteins from a Single Sample
Published on: June 1, 2017
09:01Extraction and Quantification of Soluble, Radiolabeled Inositol Polyphosphates from Different Plant Species using SAX-HPLC
Published on: June 26, 2020
Related Concept Videos
Titration in Nonaqueous Solvents
Extraction: Advanced Methods
High-Performance Liquid Chromatography: Elution Process
Analyte Adsorption and Distribution