Related Experiment Video
Updated: May 16, 2026

gP2S, an Information Management System for CryoEM Experiments
Published on: June 10, 2021
Data management and other logistical challenges for the GEMS: the data coordinating center perspective
Kousick Biswas1, Christina Carty, Rebecca Horney
1Cooperative Studies Program Coordinating Center, Department of Veterans Affairs, PO Box 1010, Perry Point, MD 21902, USA. kousick.biswas@va.gov
Insights
The Global Enteric Multicenter Study (GEMS) managed extensive data from children under five across multiple countries. This paper details the data coordinating center
Area of Science:
- Epidemiology
- Global Health
- Data Management
Background:
- The Global Enteric Multicenter Study (GEMS) is the largest epidemiological study on diarrheal diseases in children under five.
- The study was conducted across diverse geographical and geopolitical settings in 4 African and 3 Asian countries.
Purpose of the Study:
- To outline the data management, administrative, and statistical support provided by the Cooperative Studies Program Coordinating Center to the GEMS study.
- To highlight the challenges encountered in managing a large-scale, multicenter epidemiological study.
Main Methods:
- Centralized data management operations were established to handle data from multiple international sites.
- Data transfer protocols and data cleaning procedures were implemented to ensure data integrity.
- Administrative and statistical support was provided throughout the study's duration.
Main Results:
- The study successfully collected a large volume of data from the participating countries.
- The data coordinating center provided comprehensive support, enabling the study's progress.
- Geographical and geopolitical differences presented significant administrative challenges.
Conclusions:
- Effective data management is crucial for large-scale international health studies.
- Centralized coordination presents unique challenges in multicenter epidemiological research.
- The GEMS study highlights the importance of robust data support systems in global health initiatives.
Abstract:
The Cooperative Studies Program Coordinating Center provided the data management, administrative, and statistical support to the Global Enteric Multicenter Study (GEMS). The GEMS study, the largest epidemiological study in the diarrheal disease area among children <5 years of age, was carried out in 4 African countries and 3 Asian countries. Given the geographical and geopolitical differences among the countries, the administration of a centralized data management operation was a major challenge. The sheer volume of the data that were collected, regular transfer of the data to a centralized database, and the cleaning of the same also posed some challenges. This paper outlines the details of the support that the data coordinating center provided and the challenges faced during the course of the study.
Related Concept Videos
Methods of Documentation VI: Case Management Model
For example, a patient with a chronic illness...
Methods of Documentation IV: Focus Charting
It typically involves three columns for recording information:
Data Reporting and Recording
Manipulation and Analysis
Selected Data About Geographic Locations
Lattice Centering and Coordination Number
Types of Unit Cells
Imagine taking a large number of identical...

