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A case of acute myocarditis as the initial presentation of Crohn's disease
In Soo Oh1, Chang Hwan Choi, Ji Hoon Park
1Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.
Insights
A rare case highlights acute myocarditis as the first sign of Crohn's disease. This presentation involved severe cardiac dysfunction and respiratory failure in a young woman, ultimately diagnosed through gastrointestinal findings.
Area of Science:
- Cardiology
- Gastroenterology
- Immunology
Background:
- Crohn's disease is a chronic inflammatory bowel disease.
- Cardiac manifestations in Crohn's disease are uncommon.
- Acute myocarditis is inflammation of the heart muscle.
Purpose of the Study:
- To report a unique case of acute myocarditis as the initial manifestation of Crohn's disease.
- To highlight the importance of considering systemic inflammatory conditions in unexplained cardiac dysfunction.
Main Methods:
- Case report of a 19-year-old female patient.
- Clinical presentation: impaired consciousness, shock, respiratory failure.
- Diagnostic workup: cardiac biomarkers, ECG, echocardiogram, colonoscopy, rectal biopsy.
Main Results:
- Elevated cardiac troponin I and CK-MB.
- Echocardiogram revealed severely impaired left ventricular systolic function.
- Colonoscopy showed terminal ileum stenosis and rectal ulcers.
- Rectal biopsy confirmed non-caseating granulomatous inflammation.
Conclusions:
- Acute myocarditis can be the initial presentation of Crohn's disease.
- Early recognition and multidisciplinary management are crucial for favorable outcomes.
- This case underscores the systemic nature of Crohn's disease.
Abstract:
We experienced a case of acute myocarditis as the initial presentation of Crohn's disease. A 19-year-old woman was admitted with impaired consciousness, shock, and respiratory failure. She had suffered from frequent diarrhea and abdominal pain for several years. Cardiac troponin I and creatine kinase-MB fraction levels were elevated to 5.32 and 16.66 ng/mL, respectively. A 12-lead electrocardiogram showed sinus tachycardia, and a chest radiograph revealed interstitial pulmonary edema. An echocardiogram showed dilated ventricles with akinesia of the basal to apical inferoseptal, anteroseptal, anterior, and inferior left ventricular walls and severely impaired systolic function. Intensive care with inotropic support was effective, and her clinical condition gradually improved. Two weeks later, a colonoscopy revealed ulceration with stenosis in the terminal ileum and multiple aphthous ulcers in the rectum. A biopsy of the rectum revealed non-caseating granulomatous inflammation. She was diagnosed with Crohn's disease presenting with acute myocarditis.
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