Immunoglobulin kappa chain as an immunologic biomarker of prognosis and chemotherapy response in solid tumors
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Updated: May 16, 2026

08:50
Predictive Immune Modeling of Solid Tumors
Published on: February 25, 2020
Marcus Schmidt1, Patrick Micke, Mathias Gehrmann
1Department of Obstetrics and Gynecology; University Hospital; Mainz, Germany.
Oncoimmunology
|November 22, 2012
Abstract:
Infiltration of plasma cells is associated with better prognosis in breast, lung and colon cancer. Immunoglobulin κ chain (IGKC) is now available as a single, robust immune marker predicting metastasis-free survival and response to chemotherapy. This will facilitate a deeper understanding of the role of the humoral immune system in cancer development.
