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Post-operative respiratory distress following primary cleft palate repair
D Smith1, S E F H J Abdullah, A Moores
1University of Glasgow Medical School, Glasgow, Scotland, UK.
Insights
Infants undergoing cleft palate repair may experience airway issues. Pre-operative obstructive sleep apnea significantly increases the risk of post-operative respiratory distress and prolonged hospital stays, necessitating careful pre-surgical evaluation.
Area of Science:
- Pediatric Surgery
- Anesthesiology
- Otolaryngology
Background:
- Infants are obligate nasal breathers, making upper airway compromise a risk during cleft palate surgery.
- Corrective palatal surgery can lead to unplanned airway support needs in infants.
- This study focuses on children requiring unplanned airway support post-palatal repair.
Purpose of the Study:
- To investigate the association between pre-operative obstructive sleep apnea and post-operative airway complications in infants undergoing cleft palate repair.
- To identify risk factors for respiratory distress and prolonged hospital stay after palatal surgery.
Main Methods:
- Retrospective study of 157 cleft palate procedures in 43 patients (2007-2009).
- Exclusion of combined cleft lip and palate, secondary palate procedures, and pre-existing airway support.
- Analysis of post-operative outcomes including respiratory distress, oxygen requirement, and hospital stay in relation to pre-operative sleep studies.
Main Results:
- Post-operative respiratory distress and oxygen requirement were significantly associated with pre-operative obstructive sleep apnea (p = 0.001 and p = 0.015).
- Obstructive sleep apnea also significantly correlated with longer hospital stays (p = 0.002) and the need for nasopharyngeal airway insertion (p = 0.017).
- Four patients desaturated within 24 hours, and five required a nasopharyngeal airway.
Conclusions:
- Pre-operative obstructive sleep apnea is a significant predictor of post-operative airway complications and extended hospitalization after cleft palate repair.
- Pre-operative sleep investigations are recommended for all children undergoing cleft palate repair to optimize surgical timing.
- Early identification of obstructive sleep apnea can guide perioperative management and improve patient outcomes.
Introduction:
Infants are obligate nasal breathers. Cleft palate closure may result in upper airway compromise. We describe children undergoing corrective palatal surgery who required unplanned airway support.
Setting:
Tertiary referral unit.
Method:
Retrospective study (2007-2009) of 157 cleft palate procedures (70 primary procedures) in 43 patients. Exclusion criteria comprised combined cleft lip and palate, secondary palate procedure, and pre-existing airway support.
Results:
The children's mean age was 7.5 months and their mean weight 7.72 kg. Eight children were syndromic, and eight underwent pre-operative sleep studies (five positive, three negative). Post-operatively, five developed respiratory distress and four required oxygen, both events significantly associated with pre-operative obstructive sleep apnoea (p = 0.001 and 0.015, respectively). Four desaturated within 24 hours. Five required a nasopharyngeal airway. Hospital stay (mean, 4 days) was significantly associated with obstructive sleep apnoea (p = 0.002) and nasopharyngeal airway insertion (p = 0.017).
Discussion:
Pre-operative obstructive sleep apnoea correlated significantly with post-operative respiratory distress, supplementary oxygen requirement, nasopharyngeal airway insertion and hospital stay. We recommend pre-operative sleep investigations for all children undergoing cleft palate repair, to enable appropriate timing of the procedure.
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