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Diversity of Protists III

Diversity of Protists III

Rhizaria are a diverse group of unicellular protists characterized by their threadlike cytoplasmic extensions known as pseudopodia. These structures aid in both locomotion and feeding, giving Rhizaria an amoeboid appearance. Their amoeboid morphology once led to taxonomic confusion, but molecular phylogenetics has clarified their evolutionary placement and emphasized their shared use of pseudopodia despite divergent lineages.This clade comprises diverse lineages such as Chlorarachniophyta,...

Diversity of Protists IV

Diversity of Protists IV

Amoebozoa represent a diverse group of terrestrial and aquatic protists that utilize lobe-shaped pseudopodia for locomotion and feeding. This characteristic differentiates them from the Rhizaria, which possess threadlike pseudopodia. The primary classifications within Amoebozoa include gymnamoebas, entamoebas, and the plasmodial and cellular slime molds. Phylogenetic evidence indicates that Amoebozoa diverged from a lineage that ultimately gave rise to fungi and animals.Gymnamoebas and...

Diversity of Protists II

Diversity of Protists II

Alveolates are a group of organisms recognized by the presence of alveoli, which are cytoplasmic sacs located beneath the cell membrane. While their function remains uncertain, alveoli may help regulate water balance by controlling how much water enters and leaves the cell. In dinoflagellates, these structures may serve as armor plates. There are three major types of alveolates: ciliates, which move using cilia; dinoflagellates, which use flagella for movement; and apicomplexans, which are...

Diversity of Protists I

Diversity of Protists I

Excavata is a diverse group of protists that includes both chemoorganotrophic and phototrophic species, with some thriving in anaerobic environments. Among the key groups within Excavata are diplomonads and parabasalids, which are flagellated protists that lack mitochondria and chloroplasts. These microorganisms typically inhabit anoxic environments, such as the intestines of animals, where they exist either symbiotically or as parasites, relying on fermentation for energy production. Some...

Diversity of Archaea III

Diversity of Archaea III

Crenarchaeota, a prominent phylum of Archaea, is remarkable for its ability to thrive in extreme environments characterized by high temperatures and acidity. These microorganisms inhabit sulfuric hot springs, volcanic systems, and submarine hydrothermal vents, where temperatures often exceed 100°C. The unique adaptations of Crenarchaeota not only allow survival under such extreme conditions but also provide insights into the mechanisms of life in primordial Earth-like environments.Morphological...

Diversity of Archaea II

Diversity of Archaea II

Archaea, one of the three domains of life, exhibit remarkable diversity and adaptability, thriving in both extreme and moderate environments. Historically, most identified archaea have been classified into two major phyla: Euryarchaeota and Crenarchaeota. However, recent molecular studies have expanded this classification to include three additional phyla: Thaumarchaeota, Nanoarchaeota, and Korarchaeota, each exhibiting unique characteristics and ecological roles.Thaumarchaeota: Mesophiles...

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Related Experiment Video

Updated: May 16, 2026

High-throughput Measurement of Dictyostelium discoideum Macropinocytosis by Flow Cytometry

High-throughput Measurement of Dictyostelium discoideum Macropinocytosis by Flow Cytometry

Published on: September 10, 2018

DictyBase 2013: integrating multiple Dictyostelid species.

Siddhartha Basu¹, Petra Fey, Yogesh Pandit

¹Biomedical Informatics Center and Center for Genetic Medicine, Northwestern Univesity, Feinberg School of Medicine, 750 North Lake Shore Drive, Chicago, IL 60611, USA.

Nucleic Acids Research

|November 23, 2012

Summary

dictyBase has expanded to become a genome portal for Amoebozoa, now including multiple Dictyostelid species. The updated database features a new Genome Browser with RNAseq expression and cross-species comparison tools.

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Last Updated: May 16, 2026

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Area of Science:

Bioinformatics
Genomics
Computational Biology

Background:

dictyBase is the primary model organism database for Dictyostelium discoideum.
Previous updates have focused on expanding its capabilities and data scope.

Purpose of the Study:

To provide an update on the advancements and new features of dictyBase.
To highlight dictyBase's evolution into a genome portal for the Amoebozoa clade.

Main Methods:

Integration of multiple Dictyostelid genomes, including Dictyostelium purpureum, Dictyostelium fasciculatum, and Polysphondylium pallidum.
Development of a new Genome Browser incorporating RNAseq expression data.
Implementation of interspecies Basic Local Alignment Search Tool (BLAST) alignments and a unified BLAST search functionality.

Main Results:

dictyBase now hosts an expanded collection of Dictyostelid genomes.
The new Genome Browser offers visualization of RNAseq expression data.
Enhanced cross-species comparison capabilities are available through integrated BLAST tools.

Conclusions:

dictyBase has significantly advanced its role as a comprehensive genome portal for the Amoebozoa.
The new features facilitate deeper comparative genomic analysis within the Amoebozoa clade.