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Updated: May 16, 2026

Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research
Published on: October 22, 2014
Ankle/brachial index to everyone
Giuseppe Giugliano1, Anna Sannino, Linda Brevetti
1Department of Clinical Medicine and Cardiovascular and Immunological Sciences, Federico II University, via Pansini 5, 80131 Naples, Italy.
Insights
The ankle-brachial index (ABI) is a valuable tool for identifying peripheral arterial disease and predicting future cardiovascular events. This simple measurement shows promise for routine clinical practice in cardiovascular risk assessment.
Area of Science:
- Cardiology
- Vascular Medicine
- Preventive Cardiology
Background:
- Identifying subclinical atherosclerosis and cardiovascular risk is crucial.
- Early detection of vascular disease can improve patient outcomes.
Purpose of the Study:
- To evaluate the Ankle-Brachial Index (ABI) as a marker for cardiovascular risk.
- To assess the utility of ABI in identifying peripheral arterial disease.
Main Methods:
- The study focuses on the diagnostic and prognostic value of the ankle-brachial index (ABI).
- ABI measurement involves comparing blood pressure in the ankles and arms.
Main Results:
- An abnormal ABI indicates lower extremity peripheral arterial disease.
- ABI is a significant predictor of future ischemic cardiovascular events.
Conclusions:
- The ankle-brachial index (ABI) possesses desirable properties for cardiovascular risk prediction.
- ABI has the potential to become a standard measurement in routine clinical practice.
Background:
In the last years significant attention has been paid in identifying markers of subclinical atherosclerosis or of increased cardiovascular risk.
Method:
An abnormal ankle/brachial index (ABI) identifies patients affected by lower extremity peripheral arterial disease, and even more important, represents a powerful predictor of the development of future ischemic cardiovascular events.
Conclusions:
In our opinion, ABI is a cardiovascular risk prediction tool with very desirable properties that might become a routine measurement in clinical practice.
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