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Visualization of HIV-1 Gag Binding to Giant Unilamellar Vesicle (GUV) Membranes
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HIV-1 p6 - a structured to flexible multifunctional membrane-interacting protein

Sara Marie Øie Solbak1, Tove Ragna Reksten, Friedrich Hahn

  • 1Department of Chemistry and Centre for Pharmacy, University of Bergen, N-5007 Bergen, Norway.

Biochimica Et Biophysica Acta
|November 24, 2012
PubMed
Summary

The human immunodeficiency virus type 1 (HIV-1) p6 protein has a defined helical structure in hydrophobic environments, crucial for viral assembly. Phosphorylation enhances its membrane interaction, modulating Gag polyprotein binding.

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