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Updated: May 16, 2026
07:42
An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract
Published on: July 1, 2020
[Candida peritonitis: Prevalence and risk factors]
María José Hernández1, Josep Balaguer, Rocío Armero
1Servicio de Anestesiología, Reanimación y Terapéutica del Dolor, Hospital Universitario Dr. Peset, Valencia, España.
Revista Iberoamericana De Micologia
|November 24, 2012
Summary
Peritoneal candidiasis (PC) affects 17.6% of patients with peritonitis. Upper gastro-intestinal tract involvement and cardiovascular failure during surgery are key risk factors for developing PC.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Surgical Infections
Background:
- Peritoneal candidiasis (PC) diagnosis relies on positive Candida cultures and clinical symptoms.
- PC is associated with a poor prognosis, necessitating early risk factor identification and empirical treatment.
- Known risk factors include prolonged antibiotic use, nosocomial infections, female gender, upper gastro-intestinal (UGI) tract involvement, and intraoperative cardiovascular failure (CVF).
Purpose of the Study:
- To determine the prevalence of peritoneal candidiasis (PC) in a hospital setting.
- To identify risk factors associated with the development of PC.
Main Methods:
- Samples from 74 peritonitis patients were analyzed between 2007 and 2010.
- Cultures of free peritoneal fluid aspirated during surgery were performed.
Main Results:
- The prevalence of PC was found to be 17.6%.
- Candida albicans accounted for 46.15% of PC cases.
- UGI tract involvement and CVF were identified as significant risk factors.
- Age, gender, nosocomial infection, and prior antibiotic treatment were not significantly associated with PC.
Conclusions:
- The study established a PC prevalence of 17.6%.
- Key predisposing risk factors identified were UGI tract involvement and intraoperative CVF.
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