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Related Experiment Video

Updated: May 16, 2026

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

Published on: December 28, 2017

Radiotherapy for ocular tumours.

C Stannard¹, W Sauerwein, G Maree

¹Department of Radiation Oncology, Groote Schuur Hospital and University of Cape Town, Cape Town, South Africa. Clare.Stannard@uct.ac.za

Eye (London, England)

|November 24, 2012

Summary

This summary is machine-generated.

Radiotherapy offers effective ocular tumor treatment, including plaque brachytherapy and proton therapy, to destroy tumors while preserving vision. These techniques are crucial for managing various eye cancers like retinoblastoma and uveal melanoma.

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Area of Science:

Ophthalmology
Radiation Oncology
Medical Physics

Background:

Ocular tumors pose treatment challenges due to sensitive eye tissues and the need to minimize vision loss.
Radiotherapy (RT) is a key modality alongside surgery, laser, cryotherapy, and chemotherapy for ocular tumors.

Purpose of the Study:

To review the applications of various radiotherapy techniques in treating diverse ocular tumors.
To highlight the efficacy of different RT methods in achieving tumor control and preserving vision.

Main Methods:

External beam radiotherapy (EBRT) and brachytherapy (plaque, interstitial implant) are discussed.
Specific techniques include strontium-90, ruthenium-106 (Ru-106), iodine-125 (I-125) plaques, proton therapy, and electron beam therapy.
Treatment approaches are tailored based on tumor type, location (conjunctiva, retina, uvea), and extent (e.g., retinoblastoma, melanoma).

Main Results:

Plaque brachytherapy with Ru-106 or I-125 is effective for conjunctival tumors and retinoblastoma.
Proton therapy and I-125 implants can treat conjunctival tumors and uveal melanomas, sparing ocular structures.
Electron beam therapy is used for conjunctival lymphoma, and EBRT or proton therapy for advanced retinoblastoma.

Conclusions:

Radiotherapy, including brachytherapy and proton therapy, provides effective treatment options for various ocular tumors.
Technological advancements allow for precise tumor targeting, maximizing local control and visual preservation.
Treatment selection depends on tumor characteristics, aiming to balance oncologic outcomes with functional vision.