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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

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Related Experiment Video

Updated: Jun 22, 2026

Isolated Hepatic Perfusion as a Treatment for Liver Metastases of Uveal Melanoma
09:52

Isolated Hepatic Perfusion as a Treatment for Liver Metastases of Uveal Melanoma

Published on: January 25, 2015

[Enophthalmic orbital metastasis].

A Larmande, C Rossazza

    Ophthalmologica. Journal International D'Ophtalmologie. International Journal of Ophthalmology. Zeitschrift Fur Augenheilkunde
    |January 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Orbital metastases can present as enophthalmos with fibrous stroma, often linked to breast or stomach cancers. This rare presentation requires careful diagnosis in patients with a history of these primary malignancies.

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    Area of Science:

    • Ophthalmology
    • Oncology
    • Pathology

    Background:

    • Orbital metastases are rare occurrences in cancer patients.
    • Enophthalmos, a clinical sign of orbital disease, can be caused by various factors.

    Observation:

    • This study examines orbital metastases characterized by a histologically typical enophthalmos and a profuse fibrous stroma.
    • A total of 18 cases are reviewed, including 16 from existing literature and 2 personal cases.

    Findings:

    • The observed orbital metastases with enophthalmos and fibrous stroma were histologically typical.
    • These metastases were found to arise subsequent to primary squirrhous carcinoma of the breast or plastic linitis of the stomach.

    Implications:

    • This presentation highlights a specific, albeit uncommon, metastatic pattern of breast and gastric cancers.
    • Recognition of this pattern is crucial for accurate diagnosis and management of orbital lesions in cancer patients.