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Related Experiment Videos

[A sterile, regulated, pulsation-dampened precision dosing system for biomedical technics].

H Merz1, M Pandit, C Oldendorf

  • 1Universität Kaiserslautern, Fachbereich Elektrotechnik, Regelungstechnik/Signaltheorie, Kaiserslautern.

Biomedizinische Technik. Biomedical Engineering
|January 1, 1990
PubMed
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This study introduces a gravimetric control system for precise, sterile fluid metering using peristaltic pumps. The system ensures high accuracy of mass flow rates for small volumes.

Area of Science:

  • Biomedical Engineering
  • Fluid Dynamics
  • Control Systems

Context:

  • Accurate and sterile metering of small fluid volumes is critical in pharmaceutical and biomedical applications.
  • Peristaltic pumps are commonly used but introduce pulsations and can be challenging to control for precise flow rates.
  • Existing methods often lack the required accuracy or sterility for sensitive applications.

Purpose:

  • To describe a novel gravimetric control system for high-accuracy mass flow metering of small and very small flow rates.
  • To detail the implementation of a digital proportional-integral (PI) controller and digital filter for precise signal processing.
  • To propose solutions for reservoir refilling and peristaltic pump pulsation compensation.

Summary:

  • A gravimetric control system utilizing a high-precision electronic scale and a digital PI controller with a digital filter is presented.

Related Experiment Videos

  • The system achieves high accuracy in continuous, sterile metering of small flow rates delivered by peristaltic pumps.
  • The design incorporates strategies for automated reservoir refilling and compensation of pump-induced pulsations.

    • Impact:

    • Enables more precise and reliable fluid handling in sterile environments, crucial for drug delivery and bioprocessing.
    • Reduces material waste and improves process efficiency through accurate flow rate control.
    • Offers a potential solution for advanced applications requiring stringent flow rate accuracy and sterility.