Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 16, 2026

Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface
08:26

Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface

Published on: July 10, 2014

Polydopamine-induced tooth remineralization.

Yun-Zhi Zhou1, Ying Cao, Wei Liu

  • 1Stomatologic Hospital & Collage, Anhui Medical University, Hefei, 230032, China.

ACS Applied Materials & Interfaces
|November 27, 2012
PubMed
Summary

Polydopamine coating significantly enhances dentin remineralization by promoting hydroxyapatite crystal formation, offering a potential universal method for dental tissue repair.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development of a novel pH-responsive anti-caries nanocomposite hydrogel.

Journal of dentistry·2026
Same author

Antibiofilm Property of Silver Diamine Fluoride Against Elected Periodontal Pathogens: An In Vitro Study.

International dental journal·2026
Same author

Preventive effects of a strontium‑containing nano bioactive glass hydrogel against enamel caries: An in vitro study.

Journal of dentistry·2026
Same author

Association Between Consumption of Energy and Sports Drinks with Oral Health: A Systematic Review.

Dentistry journal·2026
Same author

38% silver diamine fluoride for dentine hypersensitivity treatment: an <i>in situ</i> study.

Frontiers in oral health·2026
Same author

Managing dentine erosion with silver diamine fluoride: An in situ study.

Journal of dentistry·2026

Area of Science:

  • Biomaterials Science
  • Dental Research
  • Surface Chemistry

Background:

  • Mussel-inspired dopamine is widely used for biomaterial surface modification.
  • Polydopamine coatings leverage natural bioadhesion principles for material functionalization.

Purpose of the Study:

  • To investigate the efficacy of polydopamine coating in promoting the remineralization of demineralized dental enamel and dentin.
  • To evaluate the impact of polydopamine on the formation of hydroxyapatite crystals in dental tissues.

Main Methods:

  • Demineralized dental slices (enamel and dentin) were etched with phosphoric acid.
  • Surfaces were coated with polydopamine via dopamine solution immersion.
  • Coated and uncoated samples were immersed in a calcium and phosphate supersaturated solution for remineralization.

More Related Videos

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants
08:12

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants

Published on: March 29, 2018

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice
07:07

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice

Published on: January 12, 2017

Related Experiment Videos

Last Updated: May 16, 2026

Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface
08:26

Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface

Published on: July 10, 2014

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants
08:12

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants

Published on: March 29, 2018

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice
07:07

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice

Published on: January 12, 2017

  • Characterization included SEM, XRD, FTIR, microhardness, and nanoscratch analyses.

    • Main Results:

    • Polydopamine coating showed no significant effect on enamel remineralization.
    • A significant enhancement in dentin remineralization was observed with polydopamine coating.
    • Dentin tubules were effectively occluded by densely packed hydroxyapatite crystals after coating.

    Conclusions:

    • Polydopamine coating is a promising technique for promoting dentin remineralization.
    • This method could offer a simple, universal approach for simultaneous enamel and dentin remineralization.
    • Further research may explore clinical applications of polydopamine in restorative dentistry.