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Related Experiment Video

Updated: May 16, 2026

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants

Published on: March 29, 2018

Association between low renal function and tooth loss over 5 years.

Akihiro Yoshihara¹, Masanori Iwasaki, Hideo Miyazaki

¹Department of Oral Health and Welfare, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.

|November 27, 2012

Summary

Low renal function, indicated by changes in serum cystatin C levels, is significantly associated with tooth loss in elderly women. This finding highlights a link between kidney health and oral health over time.

Keywords:

epidemiology longitudinal study renal function tooth loss

Related Experiment Videos

Last Updated: May 16, 2026

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants

Published on: March 29, 2018

Area of Science:

Gerontology
Nephrology
Dental Medicine

Background:

Kidney function declines with age, potentially impacting systemic health.
Tooth loss is a common issue in elderly populations, affecting nutrition and quality of life.

Purpose of the Study:

To investigate the longitudinal association between declining renal function and tooth loss in older women.
To identify predictors of tooth loss in this demographic.

Main Methods:

A 5-year longitudinal study involving 406 women aged 55-74.
Renal function assessed using serum cystatin C levels.
Multiple logistic regression analysis to determine factors associated with tooth loss.

Main Results:

A significant association was found between changes in serum cystatin C levels and tooth loss over 5 years (Odds Ratio = 7.70).
Other significant factors included age, baseline number of remaining teeth, clinical attachment level, and vitamin D levels.

Conclusions:

Declining renal function is linked to an increased risk of tooth loss in elderly women.
Monitoring renal function may be important for maintaining oral health in older adults.