Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Myasthenia Gravis: Overview and Treatment

Myasthenia Gravis: Overview and Treatment

Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which leads...

T Cell Types and Functions

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Maternal stress and interpersonal sensitivity during pregnancy: impact on offspring's stress and temperament.

Journal of reproductive and infant psychology·2026

Same author

Hair Cortisol Concentrations in Children: A Longitudinal Analysis Across Childhood.

Developmental psychobiology·2026

Same author

Psychological Stress, Resilience, and Social Support in Patients With Allergic Contact Dermatitis.

Dermatitis : contact, atopic, occupational, drug·2026

Same author

Impact of Allergic Contact Dermatitis on Health-Related Quality of Life: A Cross-Sectional Case-Control Study in a Spanish Population.

Contact dermatitis·2026

Same author

Psychopathological Burden in Allergic Contact Dermatitis: Results From a Case-Control Study Using the SCL-90-R.

Contact dermatitis·2026

Same author

Validation of a stress reactivity assessment protocol for children aged 4-5 years: Exploring the influence of sex, emotional responses, and crying.

Psychoneuroendocrinology·2025

Search research articles

Related Experiment Video

Updated: May 16, 2026

Application of Consistent Massage-Like Perturbations on Mouse Calves and Monitoring the Resulting Intramuscular Pressure Changes

Application of Consistent Massage-Like Perturbations on Mouse Calves and Monitoring the Resulting Intramuscular Pressure Changes

Published on: September 20, 2019

Can myofascial techniques modify immunological parameters?

Antonio Manuel Fernández-Pérez¹, Maria Isabel Peralta-Ramírez, Andrzej Pilat

¹Department of Physiotherapy, School of Health Sciences, University of Granada, Spain. fernandez@ugr.es

Journal of Alternative and Complementary Medicine (New York, N.Y.)

|November 27, 2012

Summary

Craniocervical myofascial techniques significantly increased B lymphocyte (CD19) counts in healthy males. This study demonstrates myofascial induction

Related Experiment Videos

Last Updated: May 16, 2026

Application of Consistent Massage-Like Perturbations on Mouse Calves and Monitoring the Resulting Intramuscular Pressure Changes

Application of Consistent Massage-Like Perturbations on Mouse Calves and Monitoring the Resulting Intramuscular Pressure Changes

Published on: September 20, 2019

Area of Science:

Immunology
Manual Therapy
Cellular Biology

Background:

Myofascial techniques are increasingly explored for their physiological effects.
Understanding the impact of manual therapy on immune markers is crucial.

Purpose of the Study:

To investigate the effect of specific craniocervical myofascial techniques on immunological variables.
To assess changes in lymphocyte subsets following manual therapy.

Main Methods:

Thirty-nine healthy males were randomized into an experimental (myofascial techniques) or control (rest) group.
The experimental group received suboccipital muscle release, intracranial ventricle compression, and deep cervical fascia release.
Immunological markers, including CD3, CD4, CD8, CD19, and NK cells, were measured pre- and post-intervention.

Main Results:

A significant increase in CD19 (B lymphocyte) counts was observed in the experimental group post-intervention compared to baseline.
No significant changes in CD3, CD4, CD8, or NK cell counts were found between groups.
The control group showed no significant changes in any measured immunological markers.

Conclusions:

Craniocervical myofascial induction techniques can modulate immunological variables.
Specifically, these techniques led to a significant increase in B lymphocyte counts 20 minutes post-application.
This suggests a potential role for myofascial techniques in immune response modulation.