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Updated: May 16, 2026

Non-Invasive Compression-Induced Anterior Cruciate Ligament (ACL) Injury and In Vivo Imaging of Protease Activity in Mice
Published on: September 29, 2023
Anterior cruciate ligament healing and advances in imaging
Stephen J Rabuck1, Michael G Baraga, Freddie H Fu
1Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, PA, USA. rabucksj@upmc.edu
Abstract:
Graft healing and maturation are important considerations during the rehabilitation process. Histologic studies have identified the stages of graft healing following anterior cruciate ligament (ACL) reconstruction. Correlations between histology and radiographic findings have allowed for the development of noninvasive methods to assess graft maturity. Important information regarding graft vascularity and incorporation of the graft to host bone can be obtained from imaging modalities. The role of noninvasive means in the evaluation of patients following ACL reconstruction continues to develop as these powerful tools evolve.
