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Related Experiment Video

Updated: May 16, 2026

Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling
12:29

Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling

Published on: May 30, 2011

[Arterial spin labelling: initial experience, clinical impact and difficulties].

Angelo Carneiro1, Sofia Pina, Bruno Moreira

  • 1Serviço de Neurorradiologia, Centro Hospitalar do Porto, Porto, Portugal.

Acta Medica Portuguesa
|November 27, 2012
PubMed
Summary

Arterial spin labelling (ASL) is a non-invasive MRI perfusion technique. Initial experience shows ASL provides substantial clinical information for epilepsy, neurodegenerative disorders, and tumors, despite interpretation challenges.

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Area of Science:

  • Utilizes magnetic resonance imaging (MRI) with arterial spin labelling (ASL) for non-invasive perfusion assessment.
  • Employs endogenous tracers (arterial blood protons) eliminating the need for gadolinium contrast agents.

Context:

  • ASL is an emerging MRI perfusion technique gaining clinical relevance due to robust results.
  • This study reviews initial clinical experiences with ASL over an eight-month period at 3T.

Purpose:

  • To present initial clinical experiences with ASL MRI, detailing technical aspects, applications, results, and challenges.
  • To evaluate the utility of ASL in diagnosing and characterizing neurological conditions.

Summary:

  • ASL MRI was applied to assess perfusion in epilepsy, neurodegenerative disorders, and tumors.
  • Qualitative evaluation of ASL perfusion maps revealed significant findings, including post-ictal hyperperfusion in epilepsy and characteristic hypoperfusion in neurodegenerative diseases.

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Construction and Application of Cerebral Functional Region-Based Cerebral Blood Flow Atlas Using Magnetic Resonance Imaging-Arterial Spin Labeling
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Construction and Application of Cerebral Functional Region-Based Cerebral Blood Flow Atlas Using Magnetic Resonance Imaging-Arterial Spin Labeling

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Last Updated: May 16, 2026

Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling
12:29

Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling

Published on: May 30, 2011

Construction and Application of Cerebral Functional Region-Based Cerebral Blood Flow Atlas Using Magnetic Resonance Imaging-Arterial Spin Labeling
05:23

Construction and Application of Cerebral Functional Region-Based Cerebral Blood Flow Atlas Using Magnetic Resonance Imaging-Arterial Spin Labeling

Published on: May 31, 2024

  • While not always crucial for diagnosis, ASL provided valuable supplementary information.

    • Impact:

    • ASL demonstrates potential as a valuable tool integrated into routine MRI examinations due to fast acquisition and simple post-processing.
    • Highlights the clinical utility of ASL in identifying perfusion abnormalities in various neurological conditions.
    • Identifies challenges in quantitative evaluation and clinical interpretation for future development.