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Human milk for the premature infant
1Department of Pediatrics, University of California Davis, Sacramento, CA 95817, USA. munderwood@ucdavis.edu
Insights
Mother's own milk is crucial for premature infants, improving growth and reducing serious health risks like necrotizing enterocolitis. Donor milk is an alternative but has limitations.
Area of Science:
- Neonatal nutrition and developmental pediatrics.
Background:
- Premature infants face significant health risks including growth failure, developmental delays, necrotizing enterocolitis, and late-onset sepsis.
- Human milk from mothers delivering prematurely is nutritionally superior, containing more protein and bioactive molecules.
Purpose of the Study:
- To highlight the benefits of mother's own milk for premature infants.
- To discuss the role and challenges of donor milk for premature infants.
Main Methods:
- Review of existing literature on neonatal nutrition and outcomes.
- Analysis of the nutritional composition of premature mother's milk versus donor milk.
Main Results:
- Mother's own milk significantly enhances growth and neurodevelopment in premature infants.
- Utilizing mother's own milk reduces the incidence of necrotizing enterocolitis and late-onset sepsis.
- Donor milk, while a viable option, requires pasteurization and presents nutritional and supply challenges.
Conclusions:
- Mother's own milk should be the primary enteral nutrition source for premature infants.
- Donor milk serves as a critical resource when mother's own milk is insufficient, despite its limitations.
Abstract:
Premature infants are at risk for growth failure, developmental delays, necrotizing enterocolitis, and late-onset sepsis. Human milk from women delivering prematurely has more protein and higher levels of bioactive molecules. Human milk must be fortified for premature infants to achieve adequate growth. Mother's own milk improves growth and neurodevelopment, decreases the risk of necrotizing enterocolitis and late-onset sepsis, and should be the primary enteral diet for premature infants. Donor milk is a resource for premature infants whose mothers are unable to provide an adequate supply of milk. Challenges include the need for pasteurization, nutritional and biochemical deficiencies, and limited supply.
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