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Related Concept Videos

Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
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Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...

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Updated: May 16, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
07:30

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Published on: April 23, 2021

Association between cerebral microbleeds and cognitive function: a systematic review.

Chunyan Lei1, Sen Lin, Wendan Tao

  • 1Stroke Clinical Research Unit, Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.

Journal of Neurology, Neurosurgery, and Psychiatry
|November 27, 2012
PubMed
Summary
This summary is machine-generated.

Cerebral microbleeds (MBs) are not silent; they are linked to cognitive decline. Research indicates MBs significantly impact cognitive function and may induce decline.

Keywords:
Cognition

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Last Updated: May 16, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
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06:39

Sub-acute Cerebral Microhemorrhages Induced by Lipopolysaccharide Injection in Rats

Published on: October 17, 2018

Area of Science:

  • Neurology
  • Neuroimaging
  • Gerontology

Background:

  • Cerebral microbleeds (MBs), defined as brain microvascular lesions, were traditionally considered asymptomatic.
  • Emerging evidence suggests a correlation between MBs and cognitive function decline.

Purpose of the Study:

  • To systematically review existing literature and determine the association between cerebral microbleeds and cognitive function.

Main Methods:

  • A systematic literature search was conducted across major databases (Cochrane Library, MEDLINE, EMBASE, CNKI).
  • Reference lists of relevant studies and reviews were also examined.
  • Meta-analysis (qualitative and quantitative) was performed on eligible studies.

Main Results:

  • Seven studies were included in the review.
  • Meta-analysis indicated a significant association between MBs and cognitive impairment (OR 3.06, 95% CI 1.59-5.89).
  • MBs in specific brain regions (frontal, temporal, basal ganglia) may also contribute to cognitive dysfunction.

Conclusions:

  • Cerebral microbleeds are not clinically silent.
  • MBs may act as a causative factor in cognitive function decline.